Antifibrinolytics and the Hemoabdomen: What’s the Latest Evidence?

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November 2025

In today’s VETgirl online veterinary continuing education podcast, we dig into a popular question in emergency surgery: can antifibrinolytics such as epsilon aminocaproic acid (εACA) really help slow the bleed in dogs with spontaneous hemoabdomen? A recently published prospective study takes a stab at answering it, but does the data give us clarity, or perhaps more questions? Tune in as we explore the findings, highlight key takeaways, and sort out what this might mean (or not mean) for your next case.

Resource:

Gazsi-Hull K, Goic JB, Butler AL. Use of Epsilon Aminocaproic Acid in Perioperative Stabilization of Canine Spontaneous Hemoperitoneum. Vet Emerg Crit Care. 2025. 35(3):189-196.

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